Educational aims
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Describe how genetic studies have explained a small portion of asthma heritability
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Discuss how epigenetic marks are influenced by the environment and are important in T-cell lineage differentiation
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Describe animal studies of the role of DNA methylation in the development of allergic airway disease
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Summarise human studies on the role of DNA methylation in asthma and allergy
Footnotes
Statement of Interest
None declared
This article has been modified from an ERS School Course held in Barcelona, Spain, in 2013. The original slides and material can be found at www.ers-education.org
- ©ERS 2014
Breathe articles are open access and distributed under the terms of the Creative Commons Attribution Non-Commercial Licence 4.0.