European Respiratory Society

Epigenetics and prenatal influences on asthma and allergic airways disease

Ivana V. Yang

Educational aims

  • Describe how genetic studies have explained a small portion of asthma heritability

  • Discuss how epigenetic marks are influenced by the environment and are important in T-cell lineage differentiation

  • Describe animal studies of the role of DNA methylation in the development of allergic airway disease

  • Summarise human studies on the role of DNA methylation in asthma and allergy


  • Statement of Interest

    None declared

  • This article has been modified from an ERS School Course held in Barcelona, Spain, in 2013. The original slides and material can be found at

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