Mesh nebulisers can be used to nebulise aqueous drugs and suspensions; however, with suspensions, there can be a reduction in performance in terms of aerosol output rate and inhaled mass.
Based only on in vitro studies, marketed mesh nebulisers for ambulatory patients might reduce the nebulisation time without reducing drug efficiency or overdose risk.
The effect of disinfection and cleaning on marketed mesh nebulisers’ performances remains to be assessed.
To define the differences between the new mesh nebulisers and conventional jet and ultrasonic nebulisers.
To give recommendations regarding the choice of a mesh nebuliser in order to administer a therapeutic aerosol.
Summary A nebuliser is a device that converts a liquid into aerosol droplets and must be loaded with the medication before each treatment. There are three types of nebulisers: jet nebulisers, which can nebulise all drugs and can be disposable; ultrasonic nebulisers, which are silent but can only nebulise aqueous solutions and may heat the drug; and mesh nebulisers, which can be used to nebulise aqueous solutions, but can be less efficient in nebulising suspensions. The latter are silent, portable and small. They can reduce the nebulisation time without reducing drug efficiency, but disinfecting and cleaning can be difficult.
- ©ERS 2006
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