PT - JOURNAL ARTICLE AU - Victor J. Samillan AU - Andrew J. Peacock TI - State of the art: pulmonary hypertension AID - 10.1183/20734735.001214 DP - 2014 Sep 01 TA - Breathe PG - 188--197 VI - 10 IP - 3 4099 - http://breathe.ersjournals.com/content/10/3/188.short 4100 - http://breathe.ersjournals.com/content/10/3/188.full SO - Breathe2014 Sep 01; 10 AB - Key points Pulmonary arterial hypertension is still a chronic and incurable disease The most common mutation found in familial pulmonary arterial hypertension is a defect in the bone morphogenetic protein receptor 2 gene Usually the final stage of the disease is right heart failure Educational aims To provide definitions and diagnostic methods for pulmonary hypertension To provide a general classification of pulmonary hypertension To provide an overview of the currently available treatments To provide a future vision of next-generation treatments