PT - JOURNAL ARTICLE AU - A. Bush AU - S. Elborn AU - I. Götz TI - ERS School Course Cystic Fibrosis AID - 10.1183/18106838.0104.321 DP - 2005 Jun 01 TA - Breathe PG - 321--331 VI - 1 IP - 4 4099 - http://breathe.ersjournals.com/content/1/4/321.short 4100 - http://breathe.ersjournals.com/content/1/4/321.full SO - Breathe2005 Jun 01; 1 AB - Educational aimsTo identify patients with advanced and rapidly progressive lung disease.To discuss how to best optimise standard therapies.To understand the different approaches appropriate to patients who have and have not decided that lung transplantation is an option.To detail innovative strategies which may be worth attempting if conventional means failure.Summary More than 90% of CF patients will eventually die of advanced lung disease, despite everything that has been attempted. This article will discuss strategies that can be adopted when a patient is doing badly.