TY - JOUR T1 - Novel therapies for severe asthma in children and adults JF - Breathe JO - Breathe SP - 59 LP - 62 DO - 10.1183/20734735.018917 VL - 14 IS - 1 AU - Vasiliki Delimpoura AU - Clementine Bostantzoglou AU - Norrice Liu AU - Raffaella Nenna Y1 - 2018/03/01 UR - http://breathe.ersjournals.com/content/14/1/59.abstract N2 - Asthma is a heterogeneous disease usually characterised by chronic airway inflammation. It is defined by a history of symptoms such as wheeze, shortness of breath, chest tightness and cough, along with variable airflow limitation [1]. Recently, “cluster” analyses have provided insight into specific subtypes among asthma patients, which share phenotypic characteristics.The heterogeneous nature of asthma requires personalised treatments. Monoclonal antibody treatments showed good efficacy, and should be considered when symptoms are poorly controlled despite good inhaler technique, compliance and controlled comorbidities. http://ow.ly/UWpg30hImQh ER -