Table 1 Differences in histopathology between asthma and chronic obstructive pulmonary disease (COPD) airways
AsthmaCOPD
Mast cellsIncreased and activatedNormal
Dendritic cellsIncreasedUncertain
EosinophilsIncreasedNormal
NeutrophilsNormalIncreased
LymphocytesTh2Th1, Tc1
EpitheliumOften shedPseudostratified
Goblet cellsIncreasedIncreased
Airway smooth muscleIncreasedMinimal increase
Airway vesselsIncreasedNot increased
FibrosisSubepithelialPeribronchiolar
  • Th: T-helper; Tc: T-cytotoxic.