American Journal of Obstetrics and Gynecology
ResearchObstetricsObstructive sleep apnea and the risk of adverse pregnancy outcomes
Section snippets
Database
We linked 2 nationwide, population-based datasets and used the resulting compilation for our analyses. In March 1995, Taiwan initiated its National Health Insurance (NHI) program to finance health care for all its citizens. Taiwan's NHI has a unique combination of characteristics: universal coverage, a single-payer payment system with the government as the sole insurer, unrestricted access to any medical institution of the patient's choice, and a wide variety of providers including primary care
Results
The mean age of the 4746 sampled women was 30.3 ± 4.4 years (SD; range, 14–45 years). The mean birthweight for women with OSA and women without OSA were 3063 ± 584 g (SD; range, 361–4650 g) and 3147 ± 418 g (SD; range, 1426–4760 g), respectively. Moreover, the mean gestational age for women with OSA and women without OSA were 38 ± 2.28 weeks (SD; range, 24–41 weeks) and 38 ± 1.45 weeks (SD; range, 29–43 weeks), respectively.
Table 1 reports the distribution of characteristics of mothers,
Comment
After adjusting for mother and infant characteristics, we found that mothers with OSA were 1.76, 2.31, 1.34, 1.74, 1.60, 1.63, and 3.18 times more likely than unaffected mothers to have LBW, preterm, SGA babies, CS, preeclampsia, gestational diabetes, and gestational hypertension, respectively.
Our findings parallel the conclusions of many prior studies.3, 7, 9, 12, 14, 15, 16, 17 For example, Sahin et al15 reported that fetuses of women with OSA had lower mean birthweights than those of women
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The authors report no conflict of interest.
Cite this article as: Chen Y-H, Kang J-H, Lin C-C, et al. Obstructive sleep apnea and the risk of adverse pregnancy outcomes. Am J Obstet Gynecol 2012;206:136.e1-5.