Original ArticleBlood Pressure is Elevated in Children with Primary Snoring
Section snippets
Methods
Subjects for this study were drawn from our childhood OSA epidemiologic study, which involved children age 6 to 13 years recruited from 13 schools chosen at random. Parents of these children were asked to complete a validated OSA screening questionnaire17 that stratified the children into high risk or low risk for OSA. Snoring frequency was included in the questionnaire with the following response options: never, less than 1 night per month, 1 to 2 nights per month, 1 to 2 nights per week, and
Results
A total of 619 subjects were admitted for PSG, but only 466 of them had completed the ABP recording. This was because 4 subjects were admitted for PSG every working day, but our unit only had 3 ABP recording machines. Thus, 3 of 4 subjects were randomly selected for recording, none of whom refused.
Of the 466 subjects who underwent both PSG and ABP recording, 190 nonoverweight prepubertal children (mean age, 10.0 ± 1.5 years) satisfied the inclusion criteria for this study and were included in
Discussion
Our findings demonstrate that PS is an aspect of the dose-response relationship between SDB and BP in our cohort of nonoverweight prepubertal children. Daytime and nighttime BP increased and nocturnal BP dipping decreased across the severity spectrum from no snoring to PS and to increasing OSA severity. This relationship remained statistically significant even after adjusting for age, sex, and BMI. The dose-response trends for the proportion of subjects with nighttime systolic and diastolic
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Supported by a grant from the Research Grants Council of the Hong Kong Special Administrative Region (CUHK4161/02M) and a Direct Grant for Research from The Chinese University of Hong Kong (2007.1.074). The authors declare no conflicts of interest.