Chest
Original ResearchNeoplastic DiseaseMarginal Zone B-Cell Lymphoma of Bronchus-Associated Lymphoid Tissue: Imaging Findings in 21 Patients
Section snippets
Materials and Methods
Our institutional review board approved our retrospective study with a waiver of informed consent.
Demographic Findings
Three patients had associated conditions, as follows: two patients, Sjögren syndrome; one patient, systemic lupus erythematosus. Four men were smokers (mean smoking history, 27 pack-years; range, 20 to 35 pack-years), and the remaining 17 men were nonsmokers. Nine patients had respiratory symptoms (cough, seven patients; dyspnea, four patients). In 12 asymptomatic patients, lung abnormalities were detected incidentally. For these patients, a chest CT scan was performed for the following other
Discussion
According to a study7 describing 10 cases of marginal zone B-cell lymphoma of BALT, the main patterns of lung lesions seen on CT scans were airspace consolidation or nodules containing air bronchograms within the lesions. In this study, the lesions were multiple in seven cases (70%) and bilateral in six cases (60%). In our study, a multiplicity of lesions was observed in 14 patients (70%), and bilateral disease was observed in 9 patients (43%). Moreover, in our study, CT scan findings were more
References (13)
- et al.
Bronchial-associated lymphoid tissue lymphoma: a clinical study of a rare disease
Eur J Cancer
(2004) - et al.
Positron emission tomography with fluorine-18-2-fluoro-2-deoxy-D-glucose (F18-FDG) does not visualize extranodal B-cell lymphoma of the mucosa-associated lymphoid tissue (MALT)-type
Ann Oncol
(1999) - et al.
FDG-PET scanning for detection and staging of extranodal marginal zone lymphomas of the MALT type: a report of 42 cases
Ann Oncol
(2005) - et al.
Pulmonary malignant lymphoma of mucosa-associated lymphoid tissue (MALT) arising in a pediatric HIV-positive patients
Am J Surg Pathol
(1995) - et al.
Lymphoma of bronchus-associated lymphoid tissue
AJR Am J Roentgenol
(1996) - et al.
Primary lymphomas of the lung: morphological, immunohistochemical and clinical features
Histopathology
(1990)
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Pulmonary MALT lymphoma: Imaging findings in 18 cases and the associated pathological correlations
2022, American Journal of the Medical SciencesCitation Excerpt :Chronic antigenic stimulation of BALT may induce the transformation of a variety of benign and malignant lymphoid diseases, including lymphoid interstitial pneumonia (LIP), nodular lymphoid hyperplasia (NLH), MALT lymphoma and other pulmonary lymphoproliferative diseases. MALT lymphoma constitutes a lesion comprised of monoclonal lymphocyte sheets with occasional plasma cell interspersion9,22–24 and is characterized by significant lymphoid infiltration that expands the marginal zone of reactive lymphoid follicles and forms a mass-like lesion in the bronchiolar mucosa along bronchovascular regions; 1,2,18,23 in relation to the radiological appearance of masses/nodules or mass-like areas of consolidation, these lesions tend to be in bronchovascular areas.4,6,7,9,25,26 Bronchial tissue and the surrounding parenchyma may be replaced by lymphocytes, but the bronchial wall is rarely destroyed, which could explain the air bronchograms observed on imaging.9,18
Imaging of the rare cystic lung diseases
2022, Current Problems in Diagnostic RadiologyThe bronchus-associated-lymphoid tissue (BALT) an unique lymphoid organ in man and animals
2022, Annals of AnatomyComputed tomography of diffuse lung diseases and solitary pulmonary nodules
2022, Practical Pulmonary Pathology: A Diagnostic Approach
The authors have reported to the ACCP that no significant conflicts of interest exist with any companies/organizations whose products or services may be discussed in this article.