Chest
Clinical Investigations: SarcoidosisEndobronchial Disease and Racial Differences in Pulmonary Sarcoidosis
Section snippets
MATERIALS AND METHODS
We examined the FB records from January 1988 to December 1994, which are maintained by the Pulmonary and Critical Care Medicine Service at Walter Reed Army Medical Center. Our institution is a tertiary care, referral center, which cares for both active duty military personnel and their family members from the northeastern United States and Europe and for military retirees and their spouses. The active-duty population is composed of young adults from a variety of ethnic backgrounds. Our
RESULTS
Records of 3,186 FBs performed between 1988 and 1994 were retrospectively reviewed. Charts for 202 patients with suspected sarcoidosis were further examined and 48 were eliminated because other benign or malignant diagnoses were made. This left 154 patients, of whom 122 (79.9%) had the diagnosis of sarcoidosis confirmed by tissue biopsy specimen and 32 (20.1%) whose conditions were diagnosed clinically. Patients' ages ranged from 17 to 73 years (mean±SD, 35.8 ± 0.77). There were 48 black women,
DISCUSSION
Since 1975, pulmonary physicians have utilized the FB to diagnose intrathoracic sarcoidosis.3,4,8, 9, 10, 11 After initial reports revealed a high diagnostic yield of TBBX, especially in patients with parenchymal involvement, the method of performing TBBX rapidly evolved and diagnostic efforts were focused on lung tissue. Various authors used statistical analysis to predict the number of TBBXs needed to make this diagnosis reliably.9, 10, 11
Additional diagnostic methods have been described in
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Pulmonary Manifestations of Rheumatic Diseases in Children
2021, Pediatric Clinics of North AmericaCitation Excerpt :Commonly affected organs include thoracic lymph nodes, lungs, liver, spleen, eyes, bones, joints, salivary and lacrimal glands, central nervous system, and skin. Sarcoidosis affects boys and girls equally, with an incidence in the United States estimated at 5 per 100,000 in Whites and 40 per 100,000 in African Americans.99,100 Sarcoidosis in the preschool age group presents with a triad of a granulomatous skin rash, uveitis, and arthritis, and is known as Blau syndrome.101
Geoepidemiology of Sarcoidosis
2018, Sarcoidosis: A Clinician's GuidePulmonary Complications of Childhood Rheumatic Disease
2012, Paediatric Respiratory ReviewsAirway involvement in sarcoidosis
2009, ChestPulmonary Manifestations of Rheumatoid Diseases
2009, Pulmonary Manifestations of Pediatric Diseases
Endobronchial sarcoidosis data presented at Chest 1995, October 29-Nov 2, 1995, New York, and published in CHEST; racial differences data presented at the 1996 American Thoracic Society Meeting, May 12–15, and published in Am J Respir Crit Care Med.
The findings in this report are not to be construed as an official Department of the Army position unless so designated by other authorized documents.
No financial support related to this manuscript was received by any of its authors.