Nasal intermittent positive pressure ventilation (NIPPV) can provide symptom control and improved quality of life for patients with acute and chronic respiratory failure. Many patients using a Respironics mask for NIPPV develop nasal bridge pressure sores. Two dressing were compared for effectiveness in preventing such sores. Patients using Granuflex had less skin deterioration over time compared to a comparison group and patients using Spenco Dermal.