[HTML][HTML] Gastrointestinal dysmotility in critically ill patients

…, M Giannaki, C Alexopoulou, A Proklou… - Annals of …, 2018 - ncbi.nlm.nih.gov
Gastrointestinal (GI) motility disorders are commonly present in critical illness. Up to 60% of
critically ill patients have been reported to experience GI dysmotility of some form …

[HTML][HTML] Asthma in the elderly: can we distinguish it from COPD?

EG Tzortzaki, A Proklou, NM Siafakas - Journal of allergy, 2011 - hindawi.com
Asthma in older adults affects quality of life and results in a higher hospitalization rate and
mortality. In common clinical practice, asthma in the elderly is underdiagnosed and …

Lung and diaphragm protective ventilation: a synthesis of recent data

V Karageorgos, A Proklou… - Expert Review of …, 2022 - Taylor & Francis
Introduction : To adhere to the Hippocratic Oath, to ‘first, do no harm’, we need to make every
effort to minimize the adverse effects of mechanical ventilation. Our understanding of the …

[HTML][HTML] Clinical applications of mesenchymal stem cells in chronic lung diseases

…, E Bibaki, I Lasithiotaki, A Proklou… - Biomedical …, 2018 - spandidos-publications.com
Mesenchymal stem (stromal) cells (MSCs) are multipotent stromal cells that have the ability
to modulate immune response to tissue injury and promote repair in vivo. The therapeutic …

[HTML][HTML] Driving pressure during proportional assist ventilation: an observational study

K Vaporidi, C Psarologakis, A Proklou… - Annals of Intensive …, 2019 - Springer
Background During passive mechanical ventilation, the driving pressure of the respiratory
system is an important mediator of ventilator-induced lung injury. Monitoring of driving …

Overnight desaturation in interstitial lung diseases: links to pulmonary vasculopathy and mortality

GA Margaritopoulos, A Proklou… - ERJ Open …, 2024 - Eur Respiratory Soc
Background Overnight desaturation predicts poor prognosis across interstitial lung diseases
(ILDs). The aim of the present study was to investigate whether nocturnal desaturation is …

Granule cytotoxic activity and oxidative DNA damage in smoking and nonsmoking patients with asthma

A Proklou, N Soulitzis, E Neofytou, N Rovina, E Zervas… - Chest, 2013 - Elsevier
Background Lung cytotoxic mechanisms trigger the release of perforin and granzymes,
causing oxidative DNA damage that ultimately leads to apoptosis. These effects, although …

[HTML][HTML] Investigation of telomerase/telomeres system in bone marrow mesenchymal stem cells derived from IPF and RA-UIP

KM Antoniou, GA Margaritopoulos, A Proklou… - Journal of …, 2012 - Springer
Objective Idiopathic Pulmonary Fibrosis and Rheumatoid Arthritis associated usual interstitial
pneumonia seem to have the same poor outcome as there is not an effective treatment. …

[HTML][HTML] Different Activity of the Biological Axis VEGF-Flt-1 (fms-Like Tyrosine Kinase 1) and CXC Chemokines between Pulmonary Sarcoidosis and Idiopathic …

KM Antoniou, G Soufla, A Proklou… - Journal of Immunology …, 2009 - hindawi.com
Background. We have previously shown a different local and systemic angiogenic profile of
CXC chemokines in Idiopathic Pulmonary Fibrosis (IPF) patients compared to sarcoidosis. In …

[HTML][HTML] Impaired mRNA expression of the migration related chemokine receptor CXCR4 in mesenchymal stem cells of COPD patients

K Karagiannis, A Proklou, E Tsitoura… - International Journal of …, 2017 - hindawi.com
Defective tissue repair and remodeling are main aspects of Chronic Obstructive Pulmonary
Disease (COPD) pathophysiology. Bone marrow mesenchymal stem cells (BM-MSCs) have …