An imbalance between oxidative stress and antioxidative capacity is thought to play an
important role in the development and progression of chronic obstructive pulmonary disease (…

Biological or biochemical markers (so-called biomarkers) are of potential interest for clinical
application to monitor chronic diseases. Although biomarkers are frequently used in …

The aim of the study was to determine whether zileuton, an inhibitor of 5-lipoxygenase,
attenuated bronchial hyperresponsiveness (BHR) in asthmatic subjects who had marked BHR …

… In a disposable plastic semi-microcuvette we added 400 pl of defibrinated plasma, 100 pl
of buffer A, to which substances to be tested (heparin e. g.) can be added and 60 pl of a …

… Defibrinated plasma (120 pl) was incubated with 14 pl of buffer containing 0.05 M Tiis-HCl, …
6 pl of Soybean Tiypsin Inhibitor (SBTI) solution (10 mglml) was added, together with 10 pl of …

… Aeration takes place in aeration cycles of 2 h, where the length of the aerated time during
the cycle is dependent on the hydraulic load of the system (on average, aeration takes place …

… Three complementary nationwide surveillance systems are in place to monitor carbapenem
susceptibility in the Netherlands. Routine antimicrobial susceptibility test results from …

… All five univariate risk factors except place of residence during childhood remained
statistically significantly associated in the multiple logistic regression analysis. The Benjamini–…

… The study took place in the Amersfoort region in the center of the Netherlands. In addition,
cord blood samples were taken for vitamin-D and calcium levels from the 442 and 81 Dutch/…

… Thrombotesta times (TT) were determined manually, after mixing 30 p1 of plasma into
250 pl of Thrombotesta reagent. INR values were calculated as INR = (TT,,,,,/TT,,,,,,)Io ?. …