A summary of the new GINA strategy: a roadmap to asthma control

…, ML Levy, PM O'Byrne, P Paggiaro… - European …, 2015 - Eur Respiratory Soc
Over the past 20 years, the Global Initiative for Asthma (GINA) has regularly published and
annually updated a global strategy for asthma management and prevention that has formed …

Prevalence of asthma control among adults in France, Germany, Italy, Spain and the UK

P Demoly, P Paggiaro, V Plaza… - European …, 2009 - Eur Respiratory Soc
The objectives of this article were to estimate the prevalence of asthma control and describe
the characteristics of at least well-controlled (ALWC) versus not well-controlled (NWC) …

Randomized Controlled Trials and real life studies. Approaches and methodologies: a clinical point of view.

S Saturni, F Bellini, F Braido, P Paggiaro… - Pulmonary …, 2014 - Elsevier
Randomized Controlled Trials (RCTs) are the “gold standard” for evaluating treatment
outcomes providing information on treatments “efficacy”. They are designed to test a therapeutic …

Efficacy and safety of dupilumab in patients with severe chronic rhinosinusitis with nasal polyps (LIBERTY NP SINUS-24 and LIBERTY NP SINUS-52): results from two …

…, C Hopkins, H Olze, GW Canonica, P Paggiaro… - The Lancet, 2019 - thelancet.com
Background Patients with chronic rhinosinusitis with nasal polyps (CRSwNP) generally
have a high symptom burden and poor health-related quality of life, often requiring recurring …

[HTML][HTML] Tiotropium in asthma poorly controlled with standard combination therapy

…, M Engel, R Dahl, P Paggiaro… - … England Journal of …, 2012 - Mass Medical Soc
… ml in trial 1 (P=0.01) and 154±32 ml in trial 2 (P<0.001). The predose (trough) FEV 1 also
improved in trials 1 and 2 with tiotropium, as compared with placebo: a difference of 88±31 ml (…

Multicentre randomised placebo-controlled trial of inhaled fluticasone propionate in patients with chronic obstructive pulmonary disease

PL Paggiaro, R Dahle, I Bakran, L Frith, K Hollingworth… - The Lancet, 1998 - thelancet.com
… (p<0·001, p=0·048, respectively), as did clinic FEV 1 (p<0·001), forced vital capacity (p<0·001),
and mid-expiratory flow (p… propionate treatment than with placebo (p=0·004 and p=0·016, …

Early administration of oral oseltamivir increases the benefits of influenza treatment

FY Aoki, MD Macleod, P Paggiaro… - Journal of …, 2003 - academic.oup.com
Our objective was to evaluate the benefit of early treatment of influenza illness using oral
oseltamivir. This open-label, multicentre international study investigated the relationship …

[HTML][HTML] Rescue use of beclomethasone and albuterol in a single inhaler for mild asthma

…, GW Canonica, P Maestrelli, P Paggiaro… - … England Journal of …, 2007 - Mass Medical Soc
Background Treatment guidelines recommend the regular use of inhaled corticosteroids for
patients with mild persistent asthma. We investigated whether the symptom-driven use of a …

Efficacy and safety of lebrikizumab in patients with uncontrolled asthma (LAVOLTA I and LAVOLTA II): replicate, phase 3, randomised, double-blind, placebo …

…, ED Bateman, P Kopecky, P Paggiaro… - The Lancet …, 2016 - thelancet.com
… mL (p=0·0034) in the lebrikizumab 37·5 mg group and 113 mL (p=0·0013) in the lebrikizumab
125 mg group of LAVOLTA I, and 88 mL (p=0·0139) in the 37·5 mg group and 82 mL (p=0·…

[HTML][HTML] Blood eosinophils: a biomarker of response to extrafine beclomethasone/formoterol in chronic obstructive pulmonary disease

…, J Vestbo, P Jones, A Agusti, P Paggiaro… - American journal of …, 2015 - atsjournals.org
Methods The median (quartile 1; quartile 3) baseline blood eosinophil count was 181.6 (110.4;
279.8), and the distribution of counts is shown in Figure E1 in the online supplement. The …