Transthoracic ultrasonography is still not utilized to its full potential by respiratory physicians,
despite being a well-established and validated imaging modality. It allows for an immediate …

The United Nations Millennium Development Goal of reversing the global spread of tuberculosis
by 2015 has been offset by the rampant re-emergence of drug-resistant tuberculosis, in …

Background New drugs, but also shorter, better-tolerated regimens are needed to tackle the
high global burden of tuberculosis complicated by drug resistance and retroviral disease. …

Background New antituberculosis regimens are urgently needed to shorten tuberculosis
treatment. Following on from favourable assessment in a 2 week study, we investigated a novel …

Rationale: New regimens to shorten tuberculosis treatment and manage patients with drug-resistant
tuberculosis who are infected with HIV are urgently needed. Experimental and …

Background Delamanid is one of two recently approved drugs for the treatment of multidrug-resistant
tuberculosis. We aimed to evaluate the safety and efficacy of delamanid in the first …

We prospectively investigated the diagnostic utility of the Xpert MTB/RIF ( Mycobacterium
tuberculosis /rifampin [RIF] resistance) assay in 20 cases with confirmed tuberculous pleural …

Rationale: Inadequacy of T-cell responses may result in the development of tuberculosis (TB).
Myeloid-derived suppressor cells (MDSCs) have been described as suppressors of T-cell …

Background Bedaquiline and delamanid are the first drugs of new classes registered for
tuberculosis treatment in 40 years. Each can prolong the QTc interval, with maximum effects …

To the Editor: New treatments are needed to combat the worldwide increase in resistance to
antituberculosis drugs. The outlook for patients with tuberculosis who do not show a …