Introduction High Intensity training (HIT) is a time‐effective alternative to traditional exercise
programs in adults with obesity, but the superiority in terms of improving cardiopulmonary …

The allergen challenge test has been the mainstay of diagnosis of allergic diseases for a
long time since it offers a direct proof of the clinical relevance of a particular allergen for the …

Even since the late 19th century, a relationship has been suspected between upper airway
disease and the subsequent development or aggravation of asthma symptoms. To date, it …

Background: Allergic rhinitis (AR) and asthma are characterized by means of a similar
inflammatory process in which eosinophils are important effector cells. The migration of …

Allergic rhinitis and asthma often coexist and share a genetic background. Pathophysiologic
connections between the nose and lungs are still not entirely understood. This study was …

Omalizumab has demonstrated therapeutic benefits in controlled clinical trials. Evaluation of
outcomes in real-world clinical practice is needed to provide a complete understanding of …

Epithelial cells form a tight barrier against environmental stimuli via tight junctions (TJs) and
adherence junctions (AJs). Defects in TJ and AJ proteins may cause changes in epithelial …

Mast cells and basophils are cells that play an important role in the initiation and control of
allergic inflammation in asthma and rhinitis. This study was undertaken to determine the …

Background Local airway inflammation and airway remodelling are considered important in
the clinical expression of allergic asthma. Objective The aim of this study was to compare …

Background The pathogenesis of asthma in obese subjects is poorly understood and has
been described as a specific phenotype in these patients. Weight loss improves asthma …