The significant and growing global prevalence of diabetes continues to challenge people
with diabetes (PwD), healthcare providers, and payers. While maintaining near-normal …

… For paired results at lower glucose concentrations, with capillary glucose <5.5 mmol/l (n=1468),
the mean absolute difference was 0.75 mmol/l; for paired results at higher glucose …

… Time in hypoglycaemia (⩽3.9 mmol/L) was reduced in the Libre arm from 3.38 to 2.03 h/day
(38% reduction compared with the control group; p < 0.0001). The second study is REPLACE…

Background The feasibility, safety, and efficacy of prolonged use of an artificial beta cell (closed-loop
insulin-delivery system) in the home setting have not been established. Methods In …

Background In persons with type 1 diabetes and high glycated hemoglobin levels, the benefits
of intermittently scanned continuous glucose monitoring with optional alarms for high and …

Background The achievement of glycaemic control remains challenging for patients with
type 1 diabetes. We assessed the effectiveness of day-and-night hybrid closed-loop insulin …

Physical exercise is an important component in the management of type 1 diabetes across
the lifespan. Yet, acute exercise increases the risk of dysglycaemia, and the direction of …

Background: A composite metric for the quality of glycemia from continuous glucose monitor
(CGM) tracings could be useful for assisting with basic clinical interpretation of CGM data. …

… time when adjusted sensor glucose was between 3.9 and 8.0 mmol/L from 2300 to 0700
h. … Two participants measured blood ketones >1.5 mmol/L one participant on one occasion …

OBJECTIVE To determine whether impaired awareness of hypoglycemia (IAH) can be
improved and severe hypoglycemia (SH) prevented in type 1 diabetes, we compared an insulin …