Key points Mesh nebulisers can be used to nebulise aqueous drugs and suspensions;
however, with suspensions, there can be a reduction in performance in terms of aerosol output …

… Immunoglobulin monomers consist of two light (L) chains (25 kDa) and two heavy (H) chains
(55 kDa) arranged in a Y-shape. The light chains interact with the amino-terminal part of the …

… eg, a mean flow rate of 15 L/min that was used to simulate quiet breathing in our study)
promotes aerosol losses at a HFT flow rate of 30 to 60 L/min (ie, higher than 15 L/min) because of …

… ) operating at an airflow rate of 12.0 l/min. The duration of the … at an airflow rate of 12.0 l/min.
Volumes of nebulised … of droplets at a flow rate of 15.0 l/min. The deposited aerosol on each …

… 8 L/min (combination of 6 L/min gas driving the jet nebulizer with 2 L/min NHF flow-rate or 8
L/… Beyond high gas flow driven aerosol impaction (6 L/min jet nebulization plus 2 L/min NHF …

… The MistyNeb was driven by oxygen at a flow of 6 L/min. The VMD produced by MistyNeb
was 4.6 μm (Spraytech, Malvern, UK). Maintenance of ventilator parameters required …

… L Vecellio is an employee of Nemera, a medical device company. English writing assistance,
provided by David Fraser, Biotech Communication, was utilized in the production of this …

In vitro – in vivo correlation (IVIVC) allows prediction of in vivo drug deposition from a nasally
inhaled drug based on in vitro drug measurements. In vitro measurements include physical …

Introduction: Pulmonary drug delivery is a complex field of research combining physics which
drive aerosol transport and deposition and biology which underpins efficacy and toxicity of …

… The aerosol droplets were aspirated by a constant suction pump at an airflow rate of 20 l/minute,
on the opposite side of the aerosol beam. All experiments were performed at room …