Comorbidities of COPD

…, C Person-Tacnet, C Leroyer, P Diot - European …, 2013 - Eur Respiratory Soc
By 2020, chronic obstructive pulmonary disease (COPD) will be the third cause of mortality.
Extrapulmonary comorbidities influence the prognosis of patients with COPD. Tobacco …

Nebulization as a delivery method for mAbs in respiratory diseases

R Respaud, L Vecellio, P Diot… - Expert opinion on drug …, 2015 - Taylor & Francis
Introduction: The pulmonary route is not invasive and can be used to target drugs directly to
the lungs, limiting the exposure of secondary organs. It is, thus, an attractive alternative to the …

What the pulmonary specialist should know about the new inhalation therapies

…, R Dhand, P Diot, ML Everard, I Horvath, P Navalesi… - 2011 - Eur Respiratory Soc
A collaboration of multidisciplinary experts on the delivery of pharmaceutical aerosols was
facilitated by the European Respiratory Society (ERS) and the International Society for …

European Respiratory Society Guidelines on the use of nebulizers: Guidelines prepared by a European Respiratory Society Task Force on the use of nebulizers

…, M Carone, B Dautzenberg, P Diot… - European …, 2001 - Eur Respiratory Soc
The European Respiratory Society (ERS) recognizes that there are an increasing number of
national and international guidelines for the management of asthma, chronic obstructive …

Systemic sclerosis and occupational risk factors: a case–control study

…, R Pilore, S Rogier, M Stadler, P Diot… - Occupational and …, 2002 - oem.bmj.com
Aims: A case–control study was carried out between 1998 and 2000 to investigate the
relation between systemic sclerosis and occupational exposure. Methods: Eighty cases of …

Relationship between abnormalities on high-resolution CT and pulmonary function in systemic sclerosis

…, E Asquier, JL Guilmot, E Lemarié, C Valat, P Diot - Chest, 1998 - Elsevier
… group A than in group B (p < 0.001) and there was a strong inverse correlation between
HRCT score and TLC (p < 0.005) and, in addition, between HRCT score and DLCO (p < 0.0002). …

Albuterol delivery in a model of mechanical ventilation. Comparison of metered-dose inhaler and nebulizer efficiency.

P Diot, L Morra, GC Smaldone - American journal of respiratory and …, 1995 - atsjournals.org
Using an in vitro model, we compared efficiencies of jet nebulizers and metered-dose
inhalers (MDI) with actuator devices to deliver albuterol in various conditions of mechanical …

Lipid nanocapsules: ready-to-use nanovectors for the aerosol delivery of paclitaxel

…, E Roger, M Kempf, JL Racineux, P Diot… - European journal of …, 2009 - Elsevier
Aerosol drug delivery permits the development of dose-intensification strategies in severe,
malignant lung diseases. The aim of the study was to demonstrate that the encapsulation of …

Influence of DNA on the activities and inhibition of neutrophil serine proteases in cystic fibrosis sputum

…, A Gauthier, D Bréa, F Varaigne, P Diot… - American journal of …, 2012 - atsjournals.org
Uncontrolled proteolysis by neutrophil serine proteases (NSPs) in lung secretions is a hallmark
of cystic fibrosis (CF). We have shown that the active neutrophil elastase, protease 3, and …

[HTML][HTML] Aerosol deposition in neonatal ventilation

…, D Grimbert, J Montharu, C Valat, N Behan, P Diot - Pediatric …, 2005 - nature.com
… (p = 0.001), ETT (p = 0.01), and lungs (p = 0.03), whereas observations with the APN-C
nebulizer were characterized by Y-piece (p = 0.005) and expiratory limb (p … nebulizer (p = 0.002). …