In order to develop efficient therapeutic regimes for chronic obstructive pulmonary disease (COPD),
N-acetylcysteine (NAC) has been tested as a medication which can suppress …

The prevalence of childhood obesity is increasing worldwide. One of the obesity-related
complications that has received increasing attention in recent years is sleep-disordered …

The importance of the underlying local and systemic oxidative stress and inflammation in
chronic obstructive pulmonary disease (COPD) has long been established. In view of the lack …

Background Increased oxidative stress is important in the pathogenesis of chronic
obstructive pulmonary disease (COPD). We postulated that treatment with the antioxidant N-…

Values for body surface area (BSA) are commonly used in medicine, particularly to calculate
doses of chemotherapeutic agents and index cardiac output. Various BSA formulas have …

Background Hypoglossal nerve stimulation has been demonstrated to relieve upper airway
obstruction acutely, but its effect on obstructive sleep apnea is not known. Objective To …

Objectives/Hypothesis: Previous feasibility studies have shown that electrical stimulation of
the hypoglossal nerve can improve obstructive sleep apnea (OSA). The current study …

… De Backer … De Backer … WA, Van de Heyning PH. Pilot study of a novel mandibular
advancement device for the control of snoring. Acta Otolaryngol 2004;124:628–633. …

The complexity of central breathing disturbances during sleep has become increasingly
obvious. They present as central sleep apnoeas (CSAs) and hypopnoeas, periodic breathing …

Aims: To determine the prevalence of sleep-disordered breathing (SDB) in a clinical sample
of overweight and obese children and adolescents, and to examine the contribution of fat …