Abstract
Key points
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Pulmonary arterial hypertension is still a chronic and incurable disease
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The most common mutation found in familial pulmonary arterial hypertension is a defect in the bone morphogenetic protein receptor 2 gene
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Usually the final stage of the disease is right heart failure
Educational aims
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To provide definitions and diagnostic methods for pulmonary hypertension
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To provide a general classification of pulmonary hypertension
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To provide an overview of the currently available treatments
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To provide a future vision of next-generation treatments
Footnotes
Statement of Interest
Andrew J. Peacock has received grants from Actelion and Bayer, and personal fees from Actelion, Bayer and GSK, outside of this work. Victor J. Samillan has received a long-term fellowship from the European Respiratory Society.
- ©ERS 2014
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