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The era of CFTR modulators: improvements made and remaining challenges

Sara Cuevas-Ocaña, Onofrio Laselva, Julie Avolio, Raffaella Nenna
Breathe 2020 16: 200016; DOI: 10.1183/20734735.0016-2020
Sara Cuevas-Ocaña
1Wolfson Centre for Stem Cells, Tissue Engineering and Modelling, School of Medicine, University of Nottingham Biodiscovery Institute, Nottingham, UK
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  • For correspondence: sara.cuevasocana@nottingham.ac.uk
Onofrio Laselva
2Program in Molecular Medicine, The Hospital for Sick Children, Toronto, Canada
3Dept of Physiology, University of Toronto, Toronto, Canada
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  • ORCID record for Onofrio Laselva
Julie Avolio
4Program in Translational Medicine, SickKids Research Institute, The Hospital for Sick Children, Toronto, Canada
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Raffaella Nenna
5Dept of Paediatrics, “Sapienza” University of Rome, Rome, Italy
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Article Information

vol. 16 no. 2
DOI 
https://doi.org/10.1183/20734735.0016-2020

Published By 
European Respiratory Society
Print ISSN 
1810-6838
Online ISSN 
2073-4735
History 
  • Published online September 25, 2020.

Copyright & Usage 
Copyright ©ERS 2020 Breathe articles are open access and distributed under the terms of the Creative Commons Attribution Non-Commercial Licence 4.0.

Author Information

  1. Sara Cuevas-Ocaña1⇑,
  2. Onofrio Laselva2,3,
  3. Julie Avolio4 and
  4. Raffaella Nenna5
  1. 1Wolfson Centre for Stem Cells, Tissue Engineering and Modelling, School of Medicine, University of Nottingham Biodiscovery Institute, Nottingham, UK
  2. 2Program in Molecular Medicine, The Hospital for Sick Children, Toronto, Canada
  3. 3Dept of Physiology, University of Toronto, Toronto, Canada
  4. 4Program in Translational Medicine, SickKids Research Institute, The Hospital for Sick Children, Toronto, Canada
  5. 5Dept of Paediatrics, “Sapienza” University of Rome, Rome, Italy
  1. E-mail: sara.cuevasocana{at}nottingham.ac.uk
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Vol 16 Issue 2 Table of Contents
Breathe: 16 (2)
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The era of CFTR modulators: improvements made and remaining challenges
Sara Cuevas-Ocaña, Onofrio Laselva, Julie Avolio, Raffaella Nenna
Breathe Jun 2020, 16 (2) 200016; DOI: 10.1183/20734735.0016-2020

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The era of CFTR modulators: improvements made and remaining challenges
Sara Cuevas-Ocaña, Onofrio Laselva, Julie Avolio, Raffaella Nenna
Breathe Jun 2020, 16 (2) 200016; DOI: 10.1183/20734735.0016-2020
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  • Article
    • Abstract
    • CFTR modulators currently in the clinic
    • Patient response to CFTR modulators
    • Management of CF lung infections
    • CF is not only a lung disease
    • Summary
    • Footnotes
    • References
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Subjects

  • CF and non-CF bronchiectasis
  • Pulmonary pharmacology and therapeutics
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