Figures
- Figure 1
Comparison between the SARS Coronaviridae and recent pandemic influenza strains with respect to three histological patterns of lung involvement derived from the aggregation of major available English language reports. The characteristic influenza pattern of DAD and/or bland diffuse alveolar haemorrhage (DAH) is nearly invariable across described cases, with bacterial pneumonia the principal finding in the remainder. All the influenza reports and all but a few of the Coronaviridae reports included in the calculation evaluated post mortem samples. Percentages for influenza H5N1 were derived from references tabulated in [18]. Percentages for influenza H1N1 were compiled from references [19–25]. SARS-CoV-1 percentages were derived from references tabulated in [26]. SARS-CoV-2 percentages were compiled from references [6, 17, 27–37]. BO: bronchiolitis obliterans.
Tables
- Table 1
Summary of major RCTs in ARDS that produced contradicting results
Study parameter Initial trial Year Result Subsequent trial Year Result PP Prone-Supine II [40] 2009 No impact on survival PROSEVA [41] 2013 Improved survival OLV LOVS [42] 2008 No impact on survival ART [43] 2017 Reduced survival NMBA ACURASYS [44] 2010 Improved survival ROSE [45] 2019 No impact on survival CS NHLBI [46] 2006 No impact on survival DEXA-ARDS [38] 2020 Improved survival PP: prone positioning; OLV: open-lung ventilation; NMBA: neuromuscular blocking agent; CS: corticosteroids.
