It's not all about inhaled treatment: challenges with oral therapy in paediatric respiratory medicine

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Figure 1
Treatments taken each day (including oral, subcutaneous and nebulised medication and medicines/feeds via the gastrostomy).

Table 1

Algorithm on acceptable medicine forms for different age groups

	Liquid^#	Conventional or minitablet	Multi-particulate	Orodispersible tablet	Chewable tablet
Neonates	<0.5 mL volume Neutral taste	2 mm minitablet acceptable	X	X	X
Infants	<2.5 mL volume Neutral taste	<3 mm tablet Up to 3 tablets per dose	Neutral taste	<6.5 mm tablet Neutral taste	X
Children aged 2–5 years	<2.5 mL volume Neutral taste	Up to 10 minitablets acceptable <4 mm tablet Up to 3 tablets per dose	Neutral taste	<9.5 mm tablet Neutral taste	<9.5 mm tablet Neutral taste
Children aged 6–12 years	<10 mL volume Neutral taste	<7 mm tablet Up to 3 tablets per dose	Neutral taste	<9.5 mm tablet Neutral taste	<14.7 mm tablet Neutral taste

^#: including dispersible tablet or granules for reconstitution. Information from [19].

Supplementary Material
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Supplementary table S1 EDU-0005-2021.supplement