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Symptomatic mediastinal mass in a 32-year-old male

Florit Marcuse, Marijke Rutten, Rick Schreurs, Hester A. Gietema, Prisca Theunissen, Jos G. Maessen
Breathe 2021 17: 210029; DOI: 10.1183/20734735.0029-2021
Florit Marcuse
1Dept of Pulmonology, Maastricht University Medical Center+, Maastricht, The Netherlands
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  • ORCID record for Florit Marcuse
  • For correspondence: florit.marcuse@mumc.nl
Marijke Rutten
1Dept of Pulmonology, Maastricht University Medical Center+, Maastricht, The Netherlands
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Rick Schreurs
2Dept of Cardiothoracic surgery, Maastricht University Medical Center+, Maastricht, The Netherlands
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Hester A. Gietema
3Dept of Radiology and Nuclear Medicine, Maastricht University Medical Center+, Maastricht, The Netherlands
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Prisca Theunissen
4Dept of Pathology, Maastricht University Medical Center+, Maastricht, The Netherlands
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Jos G. Maessen
2Dept of Cardiothoracic surgery, Maastricht University Medical Center+, Maastricht, The Netherlands
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    Figure 1

    Chest radiograph showing a) a posterior–anterior and b) a lateral view.

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    Figure 2

    Computed tomography of the chest at mediastinal window. a) Axial view and b) sagittal view.

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    Figure 3

    3-dimensional reconstruction (computed tomography) of the lesion, with a narrowed right intermediate bronchus as a result of compression by the lesion.

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    Figure 4

    Magnetic resonance imaging scan of the chest (axial view, T2-weighted imaging).

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    Figure 5

    A cystic lesion of 5 cm was surgically removed by video-assisted thoracic surgery.

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    Figure 6

    Histology of the resected cyst. Cyst lined by respiratory type epithelium (haematoxylin and eosin staining, scale bar = 200 µm). a) The epithelium is characterised by pseudostratified columnar and ciliated cells (haematoxylin and eosin staining, scale bar = 50 µm). b) Seromucous glands are located in the underlying fibrotic cyst wall (haematoxylin and eosin staining, scale bar = 50 µm). c) Positive cytoplasmic staining for an epithelial marker (CK AE1/AE3-immunostaining 40x magnification) and d) positive nuclear staining for a pulmonary/bronchial marker (TTF1 immunostaining, 40x magnification). e) Positive cytoplasmic staining for an epithelial marker (CK AE1/AE3-immunostaining, 40x magnification) and f) positive nuclear staining for a pulmonary/bronchial marker (TTF1 immunostaining, 40x magnification).

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Vol 17 Issue 2 Table of Contents
Breathe: 17 (2)
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Symptomatic mediastinal mass in a 32-year-old male
Florit Marcuse, Marijke Rutten, Rick Schreurs, Hester A. Gietema, Prisca Theunissen, Jos G. Maessen
Breathe Jun 2021, 17 (2) 210029; DOI: 10.1183/20734735.0029-2021

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Symptomatic mediastinal mass in a 32-year-old male
Florit Marcuse, Marijke Rutten, Rick Schreurs, Hester A. Gietema, Prisca Theunissen, Jos G. Maessen
Breathe Jun 2021, 17 (2) 210029; DOI: 10.1183/20734735.0029-2021
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