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Progress in precision medicine in cystic fibrosis: a focus on CFTR modulator therapy

Daniel H. Tewkesbury, Rebecca C. Robey, Peter J. Barry
Breathe 2021 17: 210112; DOI: 10.1183/20734735.0112-2021
Daniel H. Tewkesbury
1Manchester Adult Cystic Fibrosis Centre, Wythenshawe Hospital, Manchester University NHS Foundation Trust, Manchester, UK
2Division of Immunology, Immunity to Infection & Respiratory Medicine, University of Manchester, Manchester, UK
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Rebecca C. Robey
2Division of Immunology, Immunity to Infection & Respiratory Medicine, University of Manchester, Manchester, UK
3The North West Lung Centre, Wythenshawe Hospital, Manchester University NHS Foundation Trust, Manchester, UK
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Peter J. Barry
1Manchester Adult Cystic Fibrosis Centre, Wythenshawe Hospital, Manchester University NHS Foundation Trust, Manchester, UK
2Division of Immunology, Immunity to Infection & Respiratory Medicine, University of Manchester, Manchester, UK
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  • For correspondence: peter.barry@mft.nhs.uk
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Article Information

vol. 17 no. 4
DOI 
https://doi.org/10.1183/20734735.0112-2021

Published By 
European Respiratory Society
Print ISSN 
1810-6838
Online ISSN 
2073-4735
History 
  • Received July 22, 2021
  • Accepted November 9, 2021
  • Published online January 11, 2022.

Copyright & Usage 
Copyright ©ERS 2022 Breathe articles are open access and distributed under the terms of the Creative Commons Attribution Non-Commercial Licence 4.0.

Author Information

  1. Daniel H. Tewkesbury1,2,
  2. Rebecca C. Robey2,3 and
  3. Peter J. Barry1,2⇑
  1. 1Manchester Adult Cystic Fibrosis Centre, Wythenshawe Hospital, Manchester University NHS Foundation Trust, Manchester, UK
  2. 2Division of Immunology, Immunity to Infection & Respiratory Medicine, University of Manchester, Manchester, UK
  3. 3The North West Lung Centre, Wythenshawe Hospital, Manchester University NHS Foundation Trust, Manchester, UK
  1. Corresponding author: Peter J. Barry (peter.barry{at}mft.nhs.uk)
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Vol 17 Issue 4 Table of Contents
Breathe: 17 (4)
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Progress in precision medicine in cystic fibrosis: a focus on CFTR modulator therapy
Daniel H. Tewkesbury, Rebecca C. Robey, Peter J. Barry
Breathe Dec 2021, 17 (4) 210112; DOI: 10.1183/20734735.0112-2021

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Progress in precision medicine in cystic fibrosis: a focus on CFTR modulator therapy
Daniel H. Tewkesbury, Rebecca C. Robey, Peter J. Barry
Breathe Dec 2021, 17 (4) 210112; DOI: 10.1183/20734735.0112-2021
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Jump To

  • Article
    • Abstract
    • Abstract
    • Introduction
    • The CFTR gene and CFTR protein
    • Approaches to precision medicine in CF
    • CFTR modulators
    • Outcomes with CFTR modulators
    • Conclusions
    • Footnotes
    • References
  • Figures & Data
  • Info & Metrics
  • PDF

Subjects

  • CF and non-CF bronchiectasis
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