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Exercise and asthma: β2-agonists and the competitive athlete

L-P. Boulet, R.J. Hancox, K.D. Fitch
Breathe 2010 7: 64-71; DOI: 10.1183/18106838.0701.064
L-P. Boulet
1Institut universitaire de cardiologie et de pneumologie de Québec, Université Laval, Québec, Canada
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R.J. Hancox
2Dept of Preventive and Social Medicine, Dunedin School of Medicine, University of Otago, Dunedin,
3Dept of Respiratory Medicine, Waikato Hospital, Hamilton, New Zealand,
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K.D. Fitch
4School of Sports Science, Exercise and Health, Faculty of Life Sciences, University of Western Australia, M408 Crawley, Australia
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Abstract

Educational aims

  1. Discuss the role of inhaled β-agonists in the management of exercise-induced asthma and exercise-induced bronchoconstriction.

  2. Review the beneficial versus untoward effects of inhaled β-agonists on asthma, exercise-induced asthma and exercise-induced bronchoconstriction.

  3. Report on current and past usage of these drugs by Olympic athletes.

Summary Inhaled β-agonists effectively block exercise-induced asthma/exercise-induced bronchoconstriction (EIA/EIB). They are the treatment of choice for this condition and are used by many elite and Olympic athletes. However, regular or frequent use of inhaled β-agonists leads to an increase in the underlying severity of EIA/EIB and a reduction in their bronchoprotective and bronchodilator effects, which means that they become less effective at preventing and treating EIA/EIB. Emphasis should be placed on preventative measures and anti-inflammatory treatments such as inhaled corticosteroids in order to minimise the need for inhaled β-agonists to prevent EIA/EIB.

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Exercise and asthma: β2-agonists and the competitive athlete
L-P. Boulet, R.J. Hancox, K.D. Fitch
Breathe Sep 2010, 7 (1) 64-71; DOI: 10.1183/18106838.0701.064

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Exercise and asthma: β2-agonists and the competitive athlete
L-P. Boulet, R.J. Hancox, K.D. Fitch
Breathe Sep 2010, 7 (1) 64-71; DOI: 10.1183/18106838.0701.064
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