TY - JOUR T1 - State of the art: pulmonary hypertension JF - Breathe JO - Breathe SP - 188 LP - 197 DO - 10.1183/20734735.001214 VL - 10 IS - 3 AU - Victor J. Samillan AU - Andrew J. Peacock Y1 - 2014/09/01 UR - http://breathe.ersjournals.com/content/10/3/188.abstract N2 - Key points Pulmonary arterial hypertension is still a chronic and incurable disease The most common mutation found in familial pulmonary arterial hypertension is a defect in the bone morphogenetic protein receptor 2 gene Usually the final stage of the disease is right heart failure Educational aims To provide definitions and diagnostic methods for pulmonary hypertension To provide a general classification of pulmonary hypertension To provide an overview of the currently available treatments To provide a future vision of next-generation treatments ER -