TY - JOUR T1 - Landmark papers in respiratory medicine: Automatic quantification of emphysema and airways disease on computed tomography JF - Breathe JO - Breathe SP - 79 LP - 81 DO - 10.1183/20734735.013415 VL - 12 IS - 1 AU - Firdaus A. Mohamed Hoesein AU - Pim A. de Jong Y1 - 2016/03/01 UR - http://breathe.ersjournals.com/content/12/1/79.abstract N2 - Computed tomography (CT) of the lungs is able to visualise the lungs with submillimetre resolution and has become the reference standard for emphysema assessment in vivo. CT, a simple densitometer, can aid automatic localisation and quantification of the extent of both emphysema and airway disease, nowadays with a radiation dose of below 1 millisievert for an average 70 kg adult. In this article we will give a brief overview of the three landmark studies describing the quantification of emphysema and small and large ­airways disease on CT.Landmark studies on automatic CT quantification of the pathophysiological factors in obstructive pulmonary diseases http://ow.ly/YEKhv ER -