TY - JOUR T1 - Secondary pneumothorax in end-stage lung disease complicated by noninvasive ventilation and a persistent air leak JF - Breathe JO - Breathe SP - e119 LP - e122 DO - 10.1183/20734735.027318 VL - 14 IS - 4 AU - David J. McCracken AU - Eihab O. Bedawi AU - Maged Hassan AU - Dionisios Stavroulias AU - Najib M. Rahman Y1 - 2018/12/01 UR - http://breathe.ersjournals.com/content/14/4/e119.abstract N2 - A 75-year-old man initially presented to the respiratory service in 2012 with severe chronic obstructive pulmonary disease (COPD) defined as Global Initiative for Chronic Obstructive Lung Disease stage 3. Forced expiratory volume in 1 s (FEV1) was 1.1 L (33% predicted) with FEV1/forced vital capacity 32%. He required long-term oxygen therapy at home at 4 L·min−1 and by 2015 nocturnal high-pressure noninvasive ventilation (NIV) was required due to progressive symptomatic hypercapnic respiratory failure including a carbon dioxide tension (PCO2) of 7.9 kPa and bicarbonate of 28.3 mmol·L−1.Pneumothorax is a well-recognised complication of end-stage COPD, but the management is often complex and may be complicated by other sequelae of advanced respiratory disease including the requirement for NIV http://ow.ly/vkoJ30mB4nZ ER -