PT  - JOURNAL ARTICLE
AU  - Osasere Edebiri
AU  - Fionnuala Ní Áinle
TI  - Risk factors, diagnosis and management of venous thromboembolic disease in pregnancy
AID  - 10.1183/20734735.0018-2022
DP  - 2022 Jun 01
TA  - Breathe
PG  - 220018
VI  - 18
IP  - 2
4099  - http://breathe.ersjournals.com/content/18/2/220018.short
4100  - http://breathe.ersjournals.com/content/18/2/220018.full
SO  - Breathe2022 Jun 01; 18
AB  - Venous thromboembolism (VTE) in pregnancy is a leading cause of maternal morbidity and mortality. However, despite the significant associated clinical burden and potentially devastating societal impact, there is still a paucity of data surrounding its prevention and management. Consequently, international guideline recommendations vary widely. Exclusion of pregnant women from clinical trials in the past has contributed to knowledge gaps. However, recently published and ongoing studies demonstrate that excellent clinical trials in pregnancy are achievable. This review will discuss prevention, diagnosis and treatment of VTE in pregnancy, and will also explore priorities for future research.Educational aimsTo gain an understanding of current knowledge on risk factors for pregnancy-associated venous thromboembolism (PA-VTE).To gain an understanding of the diagnosis of PA-VTE.To review up-to-date approaches to preventing and treating PA-VTE.To discuss possible limitations in current research and areas which require improvement.Venous thromboembolism in pregnancy is a leading cause of maternal morbidity and mortality. However, individualised clinical risk assessment and recent advances in clinical prediction rules for pulmonary embolism have the potential to improve management. https://bit.ly/3mjtHg2