RT Journal Article
SR Electronic
T1 Updated definition of exercise pulmonary hypertension
JF Breathe
JO Breathe
FD European Respiratory Society
SP 220232
DO 10.1183/20734735.0232-2022
VO 18
IS 4
A1 Zeder, Katarina
A1 Olschewski, Horst
A1 Kovacs, Gabor
YR 2022
UL http://breathe.ersjournals.com/content/18/4/220232.abstract
AB In the recently published European Society of Cardiology/European Respiratory Society guidelines on the diagnosis and treatment of pulmonary hypertension (PH) the haemodynamic definitions of PH were updated and a new definition for exercise PH was introduced. Accordingly, exercise PH is characterised by a mean pulmonary arterial pressure/cardiac output (CO) slope >3 Wood units (WU) from rest to exercise. This threshold is supported by several studies demonstrating prognostic and diagnostic relevance of exercise haemodynamics in various patient cohorts. From a differential diagnostic point of view, an elevated pulmonary arterial wedge pressure/CO slope >2 WU may be suitable to identify post-capillary causes of exercise PH. Right heart catheterisation remains the gold standard to assess pulmonary haemodynamics both at rest and exercise. In this review, we discuss the evidence that led to the reintroduction of exercise PH in the PH definitions.A mean pulmonary arterial pressure/cardiac output slope >3 Wood units assessed by right heart catheterisation defines exercise pulmonary hypertension https://bit.ly/3P7MfNX