RT Journal Article
SR Electronic
T1 How to increase noninvasive ventilation effectiveness in bulbar amyotrophic lateral sclerosis patients
JF Breathe
JO Breathe
FD European Respiratory Society
SP 220266
DO 10.1183/20734735.0266-2022
VO 19
IS 1
A1 Jesus Sancho
A1 Santos Ferrer
YR 2023
UL http://breathe.ersjournals.com/content/19/1/220266.abstract
AB Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disease in which the respiratory muscles are also affected, leading to respiratory failure. Bulbar impairment develops in almost all cases during the course of the disease, becoming severe in the late stages of disease. Noninvasive ventilation (NIV) has been shown to increase survival in ALS; however, severe bulbar dysfunction has a negative impact on NIV tolerance and effectiveness. Therefore, certain steps should be taken to improve NIV outcomes in these patients including optimal ventilatory parameters, adequate interface selection, effective respiratory secretion management and control of bulbar symptoms.In ALS patients, bulbar dysfunction has a negative impact on NIV tolerance and effectiveness. Optimal ventilatory parameters, adequate interface selection, effective respiratory secretion management and control of bulbar symptoms are required. https://bit.ly/3HKOGEi