RT Journal Article
SR Electronic
T1 Respiratory complications of obesity: from early changes to respiratory failure
JF Breathe
JO Breathe
FD European Respiratory Society
SP 220263
DO 10.1183/20734735.0263-2022
VO 19
IS 1
A1 Neeraj M. Shah
A1 Georgios Kaltsakas
YR 2023
UL http://breathe.ersjournals.com/content/19/1/220263.abstract
AB Obesity is a significant and increasingly common cause of respiratory compromise. It causes a decrease in static and dynamic pulmonary volumes. The expiratory reserve volume is one of the first to be affected. Obesity is associated with reduced airflow, increased airway hyperresponsiveness, and an increased risk of developing pulmonary hypertension, pulmonary embolism, respiratory tract infections, obstructive sleep apnoea and obesity hypoventilation syndrome. The physiological changes caused by obesity will eventually lead to hypoxic or hypercapnic respiratory failure. The pathophysiology of these changes includes a physical load of adipose tissue on the respiratory system and a systemic inflammatory state. Weight loss has clear, well-defined benefits in improving respiratory and airway physiology in obese individuals.Obesity has significant and wide-ranging effects on respiratory function, and is an important contributor to morbidity and mortality https://bit.ly/3k8bGmX