RT Journal Article SR Electronic T1 Exploring the efficacy and advancements of medical pleurodesis: a comprehensive review of current research JF Breathe JO Breathe FD European Respiratory Society SP 240002 DO 10.1183/20734735.0002-2024 VO 20 IS 2 A1 Castaldo, Nadia A1 Fantin, Alberto A1 Palou-schwartzbaum, Michelangelo A1 Viterale, Giovanni A1 Crisafulli, Ernesto A1 Sartori, Giulia A1 Aujayeb, Avinash A1 Patrucco, Filippo A1 Patruno, Vincenzo YR 2024 UL http://breathe.ersjournals.com/content/20/2/240002.abstract AB This narrative review aims to provide an overview of medical pleurodesis techniques, and their indications and potential adverse effects. Pleurodesis is a procedure performed with the aim of obliterating the pleural space. It has indications in the management of both malignant and benign pleural effusions and pneumothorax. Various nonsurgical techniques exist to perform pleurodesis. The scope of this work is to review the different nonsurgical techniques and their indications. This narrative review was performed checking scientific databases for medical literature, focusing especially on the data derived from randomised controlled trials. Pleurodesis is an effective method to manage pleural effusions and pneumothorax, and minimally invasive techniques are now frequently used with good results. Further research is needed to assess the efficacy of new treatments and the possibility of using different techniques in association.This review provides an overview of medical pleurodesis techniques, their indications and potential adverse effects. It examines various nonsurgical techniques for managing pleural effusions and pneumothorax. https://bit.ly/3zuHPgkMaterials are available upon reasonable request.