Table 2

Different methods of assessing adherence

MethodAccuracy[Ref.]
Self-reportHighly inaccurate[11, 20, 21]
Validated anonymous questionnaireHighly inaccurate[11, 22]
Physician or asthma nurse assessmentHighly inaccurate[3]
Pharmacy refill rateInaccurate[3, 21]
Returned inhalers: canister weighing, dose countersFairly accurate[21]
Pharmacological methods: blood/urine drug levelsFairly accurate[23]
Exhaled nitric oxide measurementInaccurate[24]
Electronic monitoringHighly accurate[3, 21, 25]