Table 7

Recommended duration of anticoagulation treatment depending on the underlying clinical scenario

Clinical scenarioDuration of anticoagulation treatment
All patients with PEMinimum 3 months
First episode of PE secondary to major reversible factor3 months, then stop
First episode of PE and no identifiable risk factorIndefinite
First episode of PE associated with a persistent risk factor other than antiphospholipid antibody syndromeIndefinite
Recurrent PE not related to a reversible risk factor>3 months
PE on a background of antiphospholipid antibody syndromeIndefinite
First episode of PE associated with a minor transient or reversible risk factorIndefinite
Always weigh the benefits versus risks of continuing treatment as well as patient preference and reach a decision on the dose and duration of anticoagulation treatment.

Information from [6].