Investigation¶ | Frequency+ |
Blood tests including full blood count, electrolytes, urea, creatinine, metabolic panel (serum calcium, magnesium, phosphate), liver function tests, ACE level | Initial diagnosis then quarterly until stable, or monthly if on immunosuppression |
Electrocardiogram | Initial diagnosis then at least biannual |
Ophthalmological review | Annual |
Chest radiograph | Initial diagnosis |
Chest CT | Depending on progress, but perhaps at least biannual if progressive disease |
Urinalysis | Initial diagnosis, with 24 h urinary calcium |
Annual | |
Follow-up | Quarterly in active disease |
Every 12–18 months in inactive disease for >2 years | |
Some recommend at least 5 year follow-up |
#: prospective data is lacking; ¶: further investigation is warranted if abnormalities are found or dependent on symptoms; +: frequency may be increased dependent on patient symptoms and known organ involvement.