Summary of results
Medication | Incidence | Mortality |
Aspirin | No effect | No effect |
Risk reduction of 13–19% for deaths of lung cancer patients when taken ≥1.5 years (aHR# 0.81 and aHR¶ 0.87) | ||
Statins | No effect | Dose-dependent risk reduction of 23% in subjects with cumulative use for ≥1.5 years (aHR#,¶ 0.77) |
Metformin | Reduced for ever-users (aHR¶ 0.89) | Reduced risk in diabetic subjects with ≥1.5 years metformin use (aHR¶ 0.76) compared to those who did not take metformin |
Reduced in subjects with ≥1.5 years of metformin use (aHR¶ 0.44) | ||
Triple combination | Reduced for ever-users (aHR# 0.83) | Reduced for ever-users (aHR# 0.83) |
Reduced in subjects with ≥1.5 years of combination drug use (aHR# 0.49) | Reduced in subjects with ≥1.5 years of combination drug use (aHR# 0.42) |
aHR: adjusted hazard ratio. #: adjustment for age, sex, income, body mass index, smoking, alcohol comsumption and Charlson comorbidity index; ¶: additional adjustment for other medication use (e.g. aspirin use was adjusted for statin use and metformin use).