Clinical and genetic subset of eosinophilic granulomatosis with polyangiitis and anti-neutrophil cytoplasmic antibody (ANCA) status
| ANCA positive | ANCA negative | |
| Genetic association | HLA DQA1 and HLA DRB1 | GPA33 and IL-5/IRF1 |
| Pathogenesis | Vasculitis Similar to other ANCA-associated vasculitis syndromes | Eosinophilic infiltration Similar to asthma |
| Organ involvement | Glomerulonephritis Alveolar haemorrhage Peripheral neuropathy | Pulmonary infiltrates Cardiomyopathy Purpura |