TABLE 1

Pulmonary function tests, DLCO and TLC on the day of admittance, at 7 days after treatment initiation and after 6 months

ParameterOn admittance7 days after treatment initiation#After 6 months#
FEV1, L1.962.60 (+31%)2.83 (+44%)
FEV1, % pred5980 (+33%)87 (+47%)
FVC, L2.893.42 (+19%)3.83 (+32%)
FVC, % pred6982 (+18%)92 (+33%)
FEV1/FVC, %89100 (+13%)97 (+9%)
FEF25–75%, % pred3155 (+76%)58 (+87%)
DLCOcSB, %4667 (+43%)68 (+48%)
DLCOcSB/VA, %6581 (+25%)83 (+28%)
TLC, % pred7485 (+15%)85 (+15%)

FEV1: forced expiratory volume in 1 s; FVC: forced vital capacity; FEF25–75%: forced expiratory flow at 25–75% of FVC; DLCOcSB: single-breath diffusing capacity for carbon monoxide corrected for haemoglobin; VA: alveolar volume; TLC: total lung capacity. #: values in parentheses are the percentage changes compared with the day of admittance.