The effect of exercise on ventilatory function in the child with asthma

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Summary

  • 1.

    Physical exercise has two quite distinct effects on ventilatory function in the asthmatic child depending upon its duration.

  • 2.

    Exercise of short duration, 1–2 minutes, produces an increase in the forced expiratory volume within 1 minute of the end of exercise.

  • 3.

    Prolonged exercise, 8–12 minutes, produces a decrease in the forced expiratory volume which reaches a minimum value between 1 and 5 minutes after exercise and then rapidly increases towards the resting level.

  • 4.

    The level of exercise determines the degree to which these ventilatory effects are evoked.

  • 5.

    Both the increase and decrease can be minimised or abolished by preliminary broncho-dilatation with isoprenaline sulphate. This suggests that the phenomena are due to changes in the airways resistance caused by broncho-dilatation or broncho-constriction in bronchi which are already to some extent constricted.

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