Chest
Clinical InvestigationsSLEEP AND BREATHINGAn Individually Adjustable Oral Appliance vs Continuous Positive Airway Pressure in Mild-to-Moderate Obstructive Sleep Apnea Syndrome
Section snippets
Patients
Twenty patients (16 men and 4 women; mean ± SD age, 56.5 ± 10.2 years; body mass index [BMI], 31.2 ± 6.4), who had been referred to a university sleep laboratory for the diagnosis and treatment of OSAS were investigated between January 1999 and December 1999. Inclusion criteria were an AHI of 5/h minimum and 30/h maximum (mean, 17.5 ± 7.7/h) measured in two diagnostic polysomnographies, and clinical symptoms of OSAS. The patients were submitted to two diagnostic measurements to ensure that, in
Results
With CPAP, a significant improvement in the respiratory parameters (AHI, snoring, Sao2 min) and sleep quality (total number of arousals and respiration-induced arousals) was achieved at both measuring time points (first night and 6 weeks; Table 1). The AHI decreased from 17.5/h ± 7.7 to 3.5 ± 2.9/h (first night) and 3.2 ± 2.9/h (6 weeks) [p < 0.01 in each case]; the arousal index decreased from 21.8 ± 9.9 to 15 ± 7.5/h (first night) and 14.1 ± 5.1/h (6 weeks) [p < 0.05 in each case]; and the
Discussion
The ASDA recognizes intraoral appliances as an alternative to CPAP treatment of nonobstructive snoring and mild OSAS.21 These ASDA guidelines are grade C recommendations supported by level V evidence.21 Numerous devices are presently available that differ widely in terms of material, freedom of mandibular movement, amount and rigidity of dental coverage, amount of mandibular advancement, and bite opening.678910111213141516171819202229 Despite the predominantly positive results, only a few
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Efficacy of titratable mandibular advancement device versus continuous positive airway pressure therapy in the treatment of obstructive sleep apnea: A clinical crossover trial
2023, Medical Journal Armed Forces IndiaCitation Excerpt :These results contradict a study by Engleman et al,25 who observed higher patient satisfaction scores with CPAP as compared to OA even in individuals with mild OSA. However, most of the available literature advocates higher satisfaction with OAs.22,16,17,30 The results of this study are applicable to a subgroup of target population, i.e., those matching the inclusion and exclusion criteria of the study.
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