Chest
Original ResearchResponse to One-Legged Cycling in Patients With COPD
Section snippets
Subjects
Nonsmoking, clinically stable patients with COPD12 were enrolled. Patients were excluded if they were hypoxemic at rest (Pao2 < 55 mm Hg), had comorbidities that limited exercise tolerance, or were unable to provide informed consent. Healthy nonsmoking volunteers were recruited from among the health center staff. The study was approved by West Park Healthcare Centre Research Ethics Committee.
Exercise Testing
All of the 27 subjects were easily able to complete the required exercise tests, including both
Enrollment
A description of the patients completing the incremental and constant-power exercise tests is provided in Table l. All patients had a clear diagnosis of COPD,12 and all had stopped smoking at least 2 months before participation in the study. Hypothesis one was tested among nine COPD patients (group 1) who completed the incremental protocol. Hypothesis two was tested in nine other COPD patients (group 2) who completed the constant-power protocol. Nine healthy individuals completed both the
Discussion
In this report, we have studied patients with COPD with ventilatory limitation to exercise of sufficient severity for it to limit incremental exercise even when cycling with only one leg. By applying the same muscle-specific workload, with less total ventilatory load these patients tolerated constant-power exercise longer. Therefore, their total work was markedly increased. These findings have the potential to be applied to enhance the effectiveness of exercise training in patients with COPD.7
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This study was supported in part by West Park Healthcare Centre Foundation.
Reproduction of this article is prohibited without written permission from the American College of Chest Physicians (www.chestjournal.org/misc/reprints.shtml).