Chest
Volume 94, Issue 6, December 1988, Pages 1249-1253
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Clinical Investigations
Balloon Angioplasty in the Treatment of Pulmonary Hypertension Caused by Pulmonary Embolism

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We present a 30-year-old man with pulmonary hypertension after pulmonary embolism. Pulmonary angiography showed multiple stenoses in the pulmonary vascular tree. We treated four of these stenoses by balloon angioplasty in three sessions. Pulmonary artery pressure was reduced from 90/25 mm Hg (mean 46) to 78/13 mm Hg (mean 35) with concomitant increase of aortic pressure from 105/60 mm Hg (mean 75) to 134/68 mm Hg (mean 90). Pulmonary perfusion scintigraphy showed increase of perfusion in the treated segments. Two procedures were followed by transient segmental pulmonary edema, but no other complications were noted. We conclude that balloon angioplasty is a promising method of lowering pulmonary artery pressure and improving pulmonary perfusion in suitable cases of pulmonary hypertension secondary to pulmonary embolism. (Chest 1988; 94:1249-53)

Section snippets

CASE REPORT

A 30-year-old man was referred to our hospital for complete evaluation. At 25 years of age he had been treated by a physiotherapist for pain in the upper right leg. Shortly afterwards he became increasingly dyspneic. A diagnosis of pulmonary embolism was confirmed by pulmonary perfusion scintigraphy and treatment with warfarin was started. He continued to experience moderate exertional dyspnea (functional class 2). The patient had been a cigarette smoker for many years and at the time of

DISCUSSION

In the majority of cases, pulmonary embolism does not lead to significant long-term changes in pulmonary artery pressure. Most of the embolic material is dissolved by the fibrinolytic system, and after about three months no remnants of emboli are found.1, 2, 3, 4, 5, 6, 7 Sometimes—especially after recurring embolism—the fibrinolytic system is exhausted and not all emboli can be cleared. Thrombi that are already organized before they embolize are also likely to remain in the pulmonary vascular

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  • Cited by (0)

    Manuscript received February 19; revision accepted April 29.

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