Risk factors for pregnancy-associated venous thromboembolism: a review

References

[1] Ay L, Kopp HP, Brix JM, Ay C, Quehenberger P, Schernthaner GH, et al. Thrombin generation in morbid obesity: significant reduction after weight loss. J Thromb Haemost. 2010;8:759–65.10.1111/j.1538-7836.2010.03766.xSearch in Google Scholar

[2] Badeanlou L, Furlan-Freguia C, Yang G, Ruf W, Samad F. Tissue factor-protease-activated receptor 2 signaling promotes diet-induced obesity and adipose inflammation. Nat Med. 2011;17:1490–7.10.1038/nm.2461Search in Google Scholar

[3] Baglin T, Gray E, Greaves M, Hunt BJ, Keeling D, Machin S, et al. Clinical guidelines for testing for heritable thrombophilia. Br J Haematol. 2010;149:209–20.10.1111/j.1365-2141.2009.08022.xSearch in Google Scholar

[4] Bates SM, Greer IA, Middeldorp S, Veenstra DL, Prabulos AM, Vandvik PO, et al. VTE, thrombophilia, antithrombotic therapy, and pregnancy: antithrombotic therapy and prevention of thrombosis. 9th ed: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines. Chest. 2012; 141(2 Suppl):e691S–736S.10.1378/chest.11-2300Search in Google Scholar

[5] Bezemer ID, van der Meer FJ, Eikenboom JC, Rosendaal FR, Doggen CJ. The value of family history as a risk indicator for venous thrombosis. Arch Intern Med. 2009;169:610–5.10.1001/archinternmed.2008.589Search in Google Scholar

[6] Biron-Andreani C, Schved JF, Daures JP. Factor V Leiden mutation and pregnancy-related venous thromboembolism: what is the exact risk? Results from a meta-analysis. Thromb Haemost. 2006;96:14–8.10.1160/TH06-02-0086Search in Google Scholar

[7] Blondon M. Thromboprophylaxis after cesarean section: decision analysis. Thromb Res. 2011;127(Suppl 3):S9–12.10.1016/S0049-3848(11)70004-4Search in Google Scholar

[8] Brill-Edwards P, Ginsberg JS, Gent M, Hirsh J, Burrows R, Kearon C, et al. Safety of withholding heparin in pregnant women with a history of venous thromboembolism. Recurrence of Clot in This Pregnancy Study Group. N Engl J Med. 2000;343:1439–44.10.1056/NEJM200011163432002Search in Google Scholar PubMed

[9] British Committee for Standards in Haematology, Stainsby D, MacLennan S, Thomas D, Isaac J, Hamilton PJ. Guidelines on the management of massive blood loss. Br J Haematol. 2006;135:634–41.10.1111/j.1365-2141.2006.06355.xSearch in Google Scholar PubMed

[10] Bucciarelli P, Mannucci PM. The hemostatic system through aging and menopause. Climacteric. 2009;12(Suppl 1):47–51.10.1080/13697130903006365Search in Google Scholar PubMed

[11] Cantwell R, Clutton-Brock T, Cooper G, Dawson A, Drife J, Garrod D, et al. Saving mothers’ lives: reviewing maternal deaths to make motherhood safer: 2006–2008. The eighth report of the Confidential Enquiries into Maternal Deaths in the United Kingdom. BJOG. 2011;118(Suppl 1):1–203.10.1111/j.1471-0528.2010.02847.xSearch in Google Scholar PubMed

[12] Chan LY, Tam WH, Lau TK. Venous thromboembolism in pregnant Chinese women. Obstet Gynecol. 2001;98(3):471–5.Search in Google Scholar

[13] Cirillo P, De Rosa S, Pacileo M, Gargiulo A, Leonardi A, Angri V, et al. Nicotine induces tissue factor expression in cultured endothelial and smooth muscle cells. J Thromb Haemost. 2006;4:453–8.10.1111/j.1538-7836.2006.01741.xSearch in Google Scholar PubMed

[14] Coughlin SR. Thrombin signalling and protease-activated receptors. Nature. 2000;407:258–64.10.1038/35025229Search in Google Scholar PubMed

[15] Danilenko-Dixon DR, Heit JA, Silverstein MD, Yawn BP, Petterson TM, Lohse CM, et al. Risk factors for deep vein thrombosis and pulmonary embolism during pregnancy or post partum: a population-based, case-control study. Am J Obstet Gynecol. 2001;184:104–10.10.1067/mob.2001.107919Search in Google Scholar PubMed

[16] Darvall KA, Sam RC, Silverman SH, Bradbury AW, Adam DJ. Obesity and thrombosis. Eur J Vasc Endovasc Surg. 2007;33:223–33.10.1016/j.ejvs.2006.10.006Search in Google Scholar PubMed

[17] de Jong PG, Coppens M, Middeldorp S. Duration of anticoagulant therapy for venous thromboembolism: balancing benefits and harms on the long term. Br J Haematol. 2012;158:433–41.10.1111/j.1365-2141.2012.09196.xSearch in Google Scholar PubMed

[18] De Stefano V, Martinelli I, Rossi E, Battaglioli T, Za T, Mannuccio Mannucci P, et al. The risk of recurrent venous thromboembolism in pregnancy and puerperium without antithrombotic prophylaxis. Br J Haematol. 2006;135:386–91.10.1111/j.1365-2141.2006.06317.xSearch in Google Scholar PubMed

[19] Delluc A, Le Moigne E, Tromeur C, Noel-Savina E, Couturaud F, Mottier D, et al. Site of venous thromboembolism and prothrombotic mutations according to body mass index. Results from the EDITH study. Br J Haematol. 2011;154:486–91.10.1111/j.1365-2141.2011.08592.xSearch in Google Scholar PubMed

[20] Engelmann B, Massberg S. Thrombosis as an intravascular effector of innate immunity. Nat Rev Immunol. 2013;13:34–45.10.1038/nri3345Search in Google Scholar PubMed

[21] Gardiner C, Tannetta DS, Simms CA, Harrison P, Redman CW, Sargent IL. Syncytiotrophoblast microvesicles released from pre-eclampsia placentae exhibit increased tissue factor activity. PLoS One. 2011;6:e26313.10.1371/journal.pone.0026313Search in Google Scholar PubMed PubMed Central

[22] Gould MK, Garcia DA, Wren SM, Karanicolas PJ, Arcelus JI, Heit JA, et al. Prevention of VTE in nonorthopedic surgical patients: antithrombotic therapy and prevention of thrombosis, 9th ed: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines. Chest. 2012; 141(2 Suppl):e227S–77S.10.1378/chest.11-2297Search in Google Scholar PubMed PubMed Central

[23] Gris JC, Bouvier S, Molinari N, Galanaud JP, Cochery-Nouvellon E, Mercier E, et al. Comparative incidence of a first thrombotic event in purely obstetric antiphospholipid syndrome with pregnancy loss: the NOH-APS observational study. Blood. 2012;119:2624–32.10.1182/blood-2011-09-381913Search in Google Scholar PubMed

[24] Heit JA, Kobbervig CE, James AH, Petterson TM, Bailey KR, Melton LJ, 3rd. Trends in the incidence of venous thromboembolism during pregnancy or postpartum: a 30-year population-based study. Ann Intern Med. 2005;143: 697–706.10.7326/0003-4819-143-10-200511150-00006Search in Google Scholar PubMed

[25] Heit JA, Leibson CL, Ashrani AA, Petterson TM, Bailey KR, Melton LJ, 3rd. Is diabetes mellitus an independent risk factor for venous thromboembolism?: a population-based case-control study. Arterioscler Thromb Vasc Biol. 2009;29:1399–405.10.1161/ATVBAHA.109.189290Search in Google Scholar PubMed PubMed Central

[26] Hung J, Lam JY, Lacoste L, Letchacovski G. Cigarette smoking acutely increases platelet thrombus formation in patients with coronary artery disease taking aspirin. Circulation. 1995;92:2432–6.10.1161/01.CIR.92.9.2432Search in Google Scholar PubMed

[27] Jacobsen AF, Skjeldestad FE, Sandset PM. Ante- and postnatal risk factors of venous thrombosis: a hospital-based case-control study. J Thromb Haemost. 2008;6:905–12.10.1111/j.1538-7836.2008.02961.xSearch in Google Scholar PubMed

[28] Jacobsen AF, Skjeldestad FE, Sandset PM. Incidence and risk patterns of venous thromboembolism in pregnancy and puerperium-a register-based case-control study. Am J Obstet Gynecol. 2008;198:233.e1–7.10.1016/j.ajog.2007.08.041Search in Google Scholar PubMed

[29] James AH, Jamison MG, Brancazio LR, Myers ER. Venous thromboembolism during pregnancy and the postpartum period: incidence, risk factors, and mortality. Am J Obstet Gynecol. 2006;194:1311–5.10.1016/j.ajog.2005.11.008Search in Google Scholar PubMed

[30] Kane EV, Calderwood C, Dobbie R, Morris C, Roman E, Greer IA. A population-based study of venous thrombosis in pregnancy in Scotland 1980–2005. Eur J Obstet Gynecol Reprod Biol. 2013;169:223–9.10.1016/j.ejogrb.2013.03.024Search in Google Scholar PubMed

[31] Keeling D, Mackie I, Moore GW, Greer IA, Greaves M, British Committee for Standards in H. Guidelines on the investigation and management of antiphospholipid syndrome. Br J Haematol. 2012;157:47–58.10.1111/j.1365-2141.2012.09037.xSearch in Google Scholar PubMed

[32] Kopp CW, Kopp HP, Steiner S, Kriwanek S, Krzyzanowska K, Bartok A, et al. Weight loss reduces tissue factor in morbidly obese patients. Obes Res. 2003;11:950–6.10.1038/oby.2003.131Search in Google Scholar

[33] Kingdom JC, Drewlo S. Is heparin a placental anticoagulant in high-risk pregnancies? Blood. 2011;118:4780–8.10.1182/blood-2011-07-319749Search in Google Scholar

[34] Larsen TB, Johnsen SP, Gislum M, Moller CA, Larsen H, Sorensen HT. ABO blood groups and risk of venous thromboembolism during pregnancy and the puerperium. A population-based, nested case-control study. J Thromb Haemost. 2005;3:300–4.10.1111/j.1538-7836.2005.01195.xSearch in Google Scholar

[35] Larsen TB, Sorensen HT, Gislum M, Johnsen SP. Maternal smoking, obesity, and risk of venous thromboembolism during pregnancy and the puerperium: a population-based nested case-control study. Thromb Res. 2007;120:505–9.10.1016/j.thromres.2006.12.003Search in Google Scholar

[36] Lee KW, Lip GY. Effects of lifestyle on hemostasis, fibrinolysis, and platelet reactivity: a systematic review. Arch Intern Med. 2003;163:2368–92.10.1001/archinte.163.19.2368Search in Google Scholar

[37] Levi M, Toh CH, Thachil J, Watson HG. Guidelines for the diagnosis and management of disseminated intravascular coagulation. British Committee for Standards in Haematology. Br J Haematol. 2009;145:24–33.10.1111/j.1365-2141.2009.07600.xSearch in Google Scholar

[38] Lindqvist P, Dahlback B, Marsal K. Thrombotic risk during pregnancy: a population study. Obstet Gynecol. 1999;94:595–9.10.1097/00006250-199910000-00021Search in Google Scholar

[39] Liu S, Rouleau J, Joseph KS, Sauve R, Liston RM, Young D, et al. Epidemiology of pregnancy-associated venous thromboembolism: a population-based study in Canada. J Obstet Gynaecol Can. 2009;31:611–20.10.1016/S1701-2163(16)34240-2Search in Google Scholar

[40] Lussana F, Coppens M, Cattaneo M, Middeldorp S. Pregnancy-related venous thromboembolism: risk and the effect of thromboprophylaxis. Thromb Res. 2012;129:673–80.10.1016/j.thromres.2012.01.017Search in Google Scholar PubMed

[41] Macey MG, Bevan S, Alam S, Verghese L, Agrawal S, Beski S, et al. Platelet activation and endogenous thrombin potential in pre-eclampsia. Thromb Res. 2010;125:e76–81.10.1016/j.thromres.2009.09.013Search in Google Scholar PubMed

[42] McDonald AP, Meier TR, Hawley AE, Thibert JN, Farris DM, Wrobleski SK, et al. Aging is associated with impaired thrombus resolution in a mouse model of stasis induced thrombosis. Thromb Res. 2010;125:72–8.10.1016/j.thromres.2009.06.005Search in Google Scholar PubMed

[43] McLintock C, Brighton T, Chunilal S, Dekker G, McDonnell N, McRae S, et al. Recommendations for the prevention of pregnancy-associated venous thromboembolism. Aust N Z J Obstet Gynaecol. 2012;52:3–13.10.1111/j.1479-828X.2011.01357.xSearch in Google Scholar PubMed

[44] Miller GJ, Bauer KA, Cooper JA, Rosenberg RD. Activation of the coagulant pathway in cigarette smokers. Thromb Haemost. 1998;79:549–53.10.1055/s-0037-1614942Search in Google Scholar

[45] Miyakis S, Lockshin MD, Atsumi T, Branch DW, Brey RL, Cervera R, et al. International consensus statement on an update of the classification criteria for definite antiphospholipid syndrome (APS). J Thromb Haemost. 2006;4:295–306.10.1111/j.1538-7836.2006.01753.xSearch in Google Scholar PubMed

[46] Newby DE, Wright RA, Labinjoh C, Ludlam CA, Fox KA, Boon NA, et al. Endothelial dysfunction, impaired endogenous fibrinolysis, and cigarette smoking: a mechanism for arterial thrombosis and myocardial infarction. Circulation. 1999;99:1411–5.10.1161/01.CIR.99.11.1411Search in Google Scholar

[47] Ni Ainle F, O’Donnell JS, Johnson JA, Brown L, Gleeson EM, Smith OP, et al. Activated protein C N-linked glycans modulate cytoprotective signaling function on endothelial cells. J Biol Chem. 2011;286:1323–30.10.1074/jbc.M110.159475Search in Google Scholar PubMed PubMed Central

[48] Pabinger I, Grafenhofer H, Kaider A, Kyrle PA, Quehenberger P, Mannhalter C, et al. Risk of pregnancy-associated recurrent venous thromboembolism in women with a history of venous thrombosis. J Thromb Haemost. 2005;3:949–54.10.1111/j.1538-7836.2005.01307.xSearch in Google Scholar PubMed

[49] Palomo I, Alarcon M, Moore-Carrasco R, Argiles JM. Hemostasis alterations in metabolic syndrome (review). Int J Mol Med. 2006;18:969–74.10.3892/ijmm.18.5.969Search in Google Scholar

[50] Pomp ER, Lenselink AM, Rosendaal FR, Doggen CJ. Pregnancy, the postpartum period and prothrombotic defects: risk of venous thrombosis in the MEGA study. J Thromb Haemost. 2008;6:632–7.10.1111/j.1538-7836.2008.02921.xSearch in Google Scholar PubMed

[51] Reducing the risk of thrombosis and embolism during pregnancy and the puerperium. Royal College of Obstetricians and Gynaecologists Green-top Guideline No 37a; 2009.Search in Google Scholar

[52] Robertson L, Wu O, Langhorne P, Twaddle S, Clark P, Lowe GD, et al. Thrombophilia in pregnancy: a systematic review. Br J Haematol. 2006;132:171–96.10.1111/j.1365-2141.2005.05847.xSearch in Google Scholar PubMed

[53] Sauls DL, Banini AE, Boyd LC, Hoffman M. Elevated prothrombin level and shortened clotting times in subjects with type 2 diabetes. J Thromb Haemost. 2007;5:638–9.10.1111/j.1538-7836.2007.02366.xSearch in Google Scholar

[54] Sibai B, Dekker G, Kupferminc M. Pre-eclampsia. Lancet. 2005;365:785–99.10.1016/S0140-6736(05)17987-2Search in Google Scholar

[55] Silverstein MD, Heit JA, Mohr DN, Petterson TM, O’Fallon WM, Melton LJ, 3rd. Trends in the incidence of deep vein thrombosis and pulmonary embolism: a 25-year population-based study. Arch Intern Med. 1998;158:585–93.10.1001/archinte.158.6.585Search in Google Scholar

[56] Simpson EL, Lawrenson RA, Nightingale AL, Farmer RD. Venous thromboembolism in pregnancy and the puerperium: incidence and additional risk factors from a London perinatal database. BJOG. 2001;108:56–60.Search in Google Scholar

[57] Sultan AA, Tata LJ, West J, Fiaschi L, Fleming KM, Nelson-Piercy C, et al. Risk factors for first venous thromboembolism around pregnancy: a population based cohort study from the United Kingdom. Blood. 2013;121:3953–61.10.1182/blood-2012-11-469551Search in Google Scholar

[58] Sultan AA, West J, Tata LJ, Fleming KM, Nelson-Piercy C, Grainge MJ. Risk of first venous thromboembolism in and around pregnancy: a population-based cohort study. Br J Haematol. 2012;156:366–73.10.1111/j.1365-2141.2011.08956.xSearch in Google Scholar

[59] Tripodi A, Branchi A, Chantarangkul V, Clerici M, Merati G, Artoni A, et al. Hypercoagulability in patients with type 2 diabetes mellitus detected by a thrombin generation assay. J Thromb Thrombolysis. 2011;31:165–72.10.1007/s11239-010-0506-0Search in Google Scholar

[60] Tully L, Gates S, Brocklehurst P, McKenzie-McHarg K, Ayers S. Surgical techniques used during caesarean section operations: results of a national survey of practice in the UK. Eur J Obstet Gynecol Reprod Biol. 2002;102:120–6.10.1016/S0301-2115(01)00589-9Search in Google Scholar

[61] Won HS, Kim do Y, Yang MS, Lee SJ, Shin HH, Park JB. Pregnancy-induced hypertension, but not gestational diabetes mellitus, is a risk factor for venous thromboembolism in pregnancy. Korean Circ J. 2011;41:23–7.10.4070/kcj.2011.41.1.23Search in Google Scholar PubMed PubMed Central