Two unusual pathological reactions to nitrofurantoin: case reports

Histopathology. 1986 Jul;10(7):701-6. doi: 10.1111/j.1365-2559.1986.tb02523.x.

Abstract

Idiosyncratic pulmonary reactions to nitrofurantoin are not unusual, often presenting as eosinophilic pneumonia. We report two cases of uncommon pathological reactions, one resembling a hypersensitivity pneumonitis and the other mimicking a giant cell interstitial pneumonia.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Female
  • Humans
  • Inflammation
  • Lung / drug effects
  • Lung / pathology*
  • Lung Diseases / chemically induced
  • Lung Diseases / pathology
  • Lung Diseases / physiopathology
  • Male
  • Nitrofurantoin / adverse effects*
  • Nitrofurantoin / therapeutic use
  • Respiratory Function Tests
  • Urinary Tract Infections / drug therapy

Substances

  • Nitrofurantoin