Should initial treatment of small cell carcinoma include systemic chemotherapy and brain irradiation?

MeSH terms

• Brain Neoplasms / radiotherapy*
• Carcinoma, Bronchogenic / therapy*
• Carcinoma, Small Cell / complications
• Carcinoma, Small Cell / drug therapy
• Carcinoma, Small Cell / therapy
• Cyclophosphamide / therapeutic use
• Humans
• Lung Neoplasms / complications
• Lung Neoplasms / drug therapy
• Lung Neoplasms / therapy*
• Methotrexate / therapeutic use
• Neoplasm Metastasis
• Time Factors