User profiles for Akhilesh Jha

Dr Akhilesh Jha

MRC Clinician Scientist | Honorary Consultant in Respiratory Medicine
Verified email at nhs.net
Cited by 5785

Respiratory syncytial virus

A Jha, H Jarvis, C Fraser… - SARS, MERS and other …, 2016 - library.oapen.org
Respiratory syncytial virus (RSV) infection has an estimated global incidence of 33 million
cases in children younger than 5 years, with 10% requiring hospital admission and up to …

Morphing aircraft concepts, classifications, and challenges

AK Jha, JN Kudva - Smart structures and materials 2004 …, 2004 - spiedigitallibrary.org
A morphing aircraft can be defined as an aircraft that changes configuration to maximize its
performance at radically different flight conditions. These configuration changes can take …

[HTML][HTML] Obesity dysregulates the pulmonary antiviral immune response

M Almond, HA Farne, MM Jackson, A Jha… - Nature …, 2023 - nature.com
Obesity is a well-recognized risk factor for severe influenza infections but the mechanisms
underlying susceptibility are poorly understood. Here, we identify that obese individuals have …

Influenza burden, prevention, and treatment in asthma‐A scoping review by the EAACI Influenza in asthma task force

J Schwarze, P Openshaw, A Jha, SR Del Giacco… - Allergy, 2018 - Wiley Online Library
To address uncertainties in the prevention and management of influenza in people with
asthma, we performed a scoping review of the published literature on influenza burden; current …

Absorption of nasal and bronchial fluids: precision sampling of the human respiratory mucosa and laboratory processing of samples

RS Thwaites, HC Jarvis, N Singh, A Jha… - JoVE (Journal of …, 2018 - jove.com
The methods of nasal absorption (NA) and bronchial absorption (BA) use synthetic absorptive
matrices (SAM) to absorb the mucosal lining fluid (MLF) of the human respiratory tract. NA …

Increased nasal mucosal interferon and CCL13 response to a TLR7/8 agonist in asthma and allergic rhinitis

A Jha, RS Thwaites, T Tunstall, OM Kon… - Journal of Allergy and …, 2021 - Elsevier
Background Acute respiratory viral infections are a major cause of respiratory morbidity and
mortality, especially in patients with preexisting lung diseases such as asthma. Toll-like …

Topical TMPRSS2 inhibition prevents SARS-CoV-2 infection in differentiated human airway cultures

…, TWM Crozier, M Coates, A Jha… - Life Science …, 2022 - life-science-alliance.org
Background: There are limited effective prophylactic/early treatments for severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. Viral entry requires spike protein …

First-and second-order flux difference splitting schemes for dam-break problem

AK Jha, J Akiyama, M Ura - Journal of Hydraulic Engineering, 1995 - ascelibrary.org
The first-order flux difference splitting scheme and its second-order extensions are investigated
for their applicability to dam-break problems. Roe's first-order explicit scheme is first …

Free vibration analysis of an inflated toroidal shell

AK Jha, DJ Inman, RH Plaut - J. Vib. Acoust., 2002 - asmedigitalcollection.asme.org
Free vibration analysis of a free inflated torus of circular cross-section is presented. The
shell theory of Sanders, including the effect of pressure, is used in formulating the governing …

An atomistic-based interphase zone model for crystalline solids

S Li, X Zeng, B Ren, J Qian, J Zhang, AK Jha - Computer Methods in …, 2012 - Elsevier
In this paper, we present an atomistic-based interphase zone model (AIZM), discuss its
physical foundation, and apply it to simulate fractures at small scales. The main technical …